Epstein barr virus ppt

Typical symptoms of infectious mononucleosis include— extreme fatigue fever sore throat head and body aches swollen lymph nodes in the neck and armpits swollen liver or spleen or both rash.

EBV is spread by saliva through— kissing sharing drinks and food using the same cups, eating utensils, or toothbrushes having contact with toys that children have drooled on. El virus de Epstein-Barr y la mononucleosis infecciosa: Lo que debe saber. Links with this icon indicate that you are leaving the CDC website. Linking to a non-federal website does not constitute an endorsement by CDC or any of its employees of the sponsors or the information and products presented on the website.

You will be subject to the destination website's privacy policy when you follow the link. Most people get infected with EBV at some point in their lives. EBV spreads most commonly through bodily fluids, primarily saliva. EBV can cause infectious mononucleosis , also called mono, and other illnesses. Many people become infected with EBV in childhood. EBV infections in children usually do not cause symptoms, or the symptoms are not distinguishable from other mild, brief childhood illnesses.

People who get symptoms from EBV infection, usually teenagers or adults, get better in two to four weeks. However, some people may feel fatigued for several weeks or even months. After you get an EBV infection, the virus becomes latent inactive in your body.

In some cases, the virus may reactivate. This does not always cause symptoms, but people with weakened immune systems are more likely to develop symptoms if EBV reactivates. EBV spreads most commonly through bodily fluids, especially saliva. However, EBV can also spread through blood and semen during sexual contact, blood transfusions, and organ transplantations. EBV can be spread by using objects, such as a toothbrush or drinking glass, that an infected person recently used.

The virus probably survives on an object at least as long as the object remains moist. Homologous recombinational repair factors are recruited and loaded onto the viral DNA genome in Epstein—Barr virus replication compartments. J Virol 83 : — Establishment of an oriP replicon is dependent upon an infrequent, epigenetic event.

Mol Cell Biol 21 : — Proc Natl Acad Sci 94 : — J Virol 82 : — The linking regions of EBNA1 are essential for its support of replication and transcription. Mol Cell Biol 19 : — Mapping EBNA-1 domains involved in binding to metaphase chromosomes. J Virol 73 : — Tetrameric ring formation of Epstein—Barr virus polymerase processivity factor is crucial for viral replication. J Virol 84 : — EMBO J 26 : — PLoS Biol 2 : e Initiation of DNA replication within oriP is dispensable for stable replication of the latent Epstein—Barr virus chromosome after infection of established cell lines.

RNA-dependent recruitment of the origin recognition complex. EMBO J 27 : — Science : — J Virol 70 : — J Cell Sci : — Transient increases in presponsible gene expression at early stages of Epstein—Barr virus productive replication. Cell Cycle 9 : — Medline Google Scholar. EMBO J 12 : — Medline Web of Science Google Scholar.

J Virol 67 : — Human origin recognition complex binds to the region of the latent origin of DNA replication of Epstein—Barr virus.

EMBO J 20 : — Genome replication and progeny virion production of herpes simplex virus type 1 mutants with temperature-sensitive lesions in the origin-binding protein. Metaphase chromosome tethering is necessary for the DNA synthesis and maintenance of oriP plasmids but is insufficient for transcription activation by Epstein—Barr nuclear antigen 1.

Erratum in J Virol , The amino terminus of Epstein—Barr virus EBV nuclear antigen 1 contains AT hooks that facilitate the replication and partitioning of latent EBV genomes by tethering them to cellular chromosomes. J Virol 29 : — Requirement of replication licensing for the dyad symmetry element-dependent replication of the Epstein—Barr virus oriP minichromosome.

Virology : 42 — Chromatin organization of gammaherpesvirus latent genomes. Biochim Biophys Acta : — Tsurumi T Tsurumi T. EBV replication enzymes. Curr Top Microbiol Immunol : 65 — Functional expression and characterization of the Epstein—Barr virus DNA polymerase catalytic subunit. Lymphomas differ in their dependence on Epstein—Barr virus.

Blood : — Identifying a property of origins of DNA synthesis required to support plasmids stably in human cells. Essential elements of a licensed, mammalian plasmid origin of DNA synthesis. Mol Cell Biol 26 : — Recruitment of cellular recombination and repair proteins to sites of herpes simplex virus type 1 DNA replication is dependent on the composition of viral proteins within prereplicative sites and correlates with the induction of the DNA damage response.

Separation of the DNA replication, segregation, and transcriptional activation functions of Epstein—Barr nuclear antigen 1. J Virol 76 : — Epstein—Barr virus DNA replication.

In DNA replication in eukaryotic cells ed. ML DePamphilis , pp. The minimal replicator of Epstein—Barr virus oriP. Virology : 22 — Cell cycle regulation of chromatin at an origin of DNA replication. EMBO J 24 : — This Article doi: Article Category Perspective Virology. Services Alert me when this article is cited Alert me if a correction is posted Similar articles in this journal Similar articles in Web of Science Similar articles in PubMed Download to citation manager Permissions.

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